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In 1998, Pfizer introduced oral medication for erectile dysfunction worldwide known as Viagra (sildenafil citrate). Despite the upheaval that brought, at both the professional and popular media and, at first sales were not expected and the acceptance by the patients was with some trepidation and reluctance. The lack of general practitioners and many specialists also got his.

As a result of sexual arousal is released from neurons (NANC) from the corpora cavernosa and the inner cells of the arteries (endothelial cells), a gaseous substance called nitric oxide (NO). This will promote a series of changes that result (mediated by cyclic-cGMP-guanosimonofosfato) in a cavernous smooth muscle relaxation, allowing vasodilation of penile arteries and the subsequent erection. But the cGMP is degraded by an enzyme, phosphodiesterase type 5 (PDE 5), responsible for the loss of erection. Sildenafil is a potent inhibitor, highly selective for PDE 5, which is opposed to the degradation of cGMP, thereby preventing penile detumescence.

 
It seems that, and so says Dr. Frank Sommer (Cologne, Germany), each night taking Viagra improves erectile function because, besides inhibiting the enzyme phosphodiesterase-5-responsible for the loss of erection ( as Viagra, by inhibiting the enzyme inhibitor, promotes the achievement and maintenance of rigidity) - would have beneficial effects on arterial endothelial cells (cells lining the inside of the arteries).

We know that the erections are due to the opening of the small arteries and cavernous smooth muscle relaxation mediated by nitric oxide, vasodilator gas, which is produced in certain neurons and in that endothelium.  with respect to their efficacy and safety validation studies seriously or double blind tests (to rule out the placebo effect) or scientific protocols in the style of Viagra or other drugs that two laboratories (Bayer and Lilly) will draw probably on sale in 2002. So the cream is not a prescription drug.
 


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After a few years in the market, and their emergence has led to prejudice and false beliefs, which were eliminated. In the early stages of research and clinical use, has proven highly effective with few side effects. Today, sildenafil citrate, known as Viagra has become one of the most used drugs, and that in recent years, its worldwide sales rose a dizzying manner.

Commotion by the appearance of the famous pill, which was originally developed Viagra (sildenafil citrate) as a treatment for heart problems. However, later studies showed that this pill also increased blood flow to the penis, so quickly was considered effective for the treatment of erectile dysfunction (impotence). Viagra was approved by the Agency of food and medicine in the United States in 1998.

Since then it has become popular, and today is available in over 90 countries.  Has proven effective in treating impotence.
 

This may be caused by aging, vascular disease, diabetes, prostate operations, spinal cord injuries and even have psychological origins. Sildenafil, which is marketed under the name Viagra, favors the increase of blood supply to the penis, causing erection. But this drug only works when the man is sexually aroused. Despite the upheaval that brought the advent of Viagra, in the medical, media and popular at first sales were not expected and the acceptance by the patients was with some trepidation and reluctance. However, sildenafil is a drug, both in the stages of research and in clinical use, has proven highly effective with few side effects.

It is important to note that this is a drug for a specific medical and psychological condition: erectile dysfunction. Although there are people who use it to improve sexual performance, and is even being considered for use in women.  





Along with the emergence of Viagra media began reporting the deaths allegedly attributed to the product. Should be clarified, in addition to bad that some patients make use of any drug, the FDA (Food and Drug Administration) requires a report every time you get a new drug on the onset of disability, death, injury and side effects those who are taking, whether or not caused by it.  In the past two years has noticed the ease with which certain drugs are purchased over the Internet, and Viagra is the most sold through this channel. This really is a danger because they can be sold to patients for whom is not indicated, causing health problems or simply not giving results.

When to take
A complete medical examination and review of the patient's medical history should be performed to determine a diagnosis of erectile dysfunction, and so detect and identify probable causes appropriate treatment. For most patients, we recommend a dose of 50 mg, which should be eaten an hour before sexual activity. However, Viagra can be taken anytime within a range from four hours to half an hour before intercourse. The maximum dose can reach 100 mg or decreased to 25 mg, but the maximum recommended dose is once daily, no more.

Benefits of Viagra
Mainly, Viagra helps to regain confidence in sexuality and sexual relationships of men suffering from erectile dysfunction. Allows you to have and maintain an erection, orgasm, and restore the pleasure during sexual encounter. These benefits improve the quality of life and interpersonal relationships.










An experience with Viagra narrated by a protagonist . As told in a letter he wrote during treatment and asked was published in time for a graphic medium and now to this page) My problem began about two years ago when I started dating a girl I liked. The first time we went to bed I felt like I was not going to make it, but I went anyway. And as is the case had failed. I wanted to kill. The truth is that she loved me. That day I justified myself by saying that he was very tired, I was going through a time of stress. She understood and we left the hotel as they had entered. I had been worried but not really ever had happened in isolation, especially the first time but only after I was recovering. I kept dating the same girl with whom we were very cool and I tried again. I admit that I wanted to test. Already in previous situations was afraid of not being able, I was obsessed that I needed to achieve erection yes or yes. That day I became something different: he had an erection but when I wanted to put on prophylactic I fell, I made the final end to her otherwise but could not penetrate. I felt bad and thought I would never be able to do with it. In that week I tried with another girl, a friend who was in a long time and had no problems, thus I came to think if I did not like it much, if not my type. On the other hand did not want to lose.

I tried again and, sometimes, I could penetrate, half embarrassed that I was not down, but just fast. A disaster! I want to clarify that women like me but in that moment I crossed some strange fantasies ... I told a doctor advised me to a urologist who gave me some pills (prepared in pharmacy) ... at the beginning it seemed that would work ... I felt more confident and one day I had a pretty good relationship, I mean I could penetrate, but it was something rather short. Then I fell again. She came to complain that I did not have in mind, that did not want ... something that was not true. It happened almost a year from bad to worse ... in the end avoided the sexual encounter with various excuses, preferred not to have to spend the showy, because I got mad. I thought about leaving because I was with another girl, what happens is that my friend did not interest me much .. and if I tried to masturbate had good erections. For the booklet of my social work consultation to another urologist who gave me a test with a shot that impressed me: there I had a doctor supererección and told me that I could inject me. No way I could have done ....

So I decided to consult a sexologist who was known to my family and was a fairly renowned psychiatrist. The truth is that I was an embarrassment barbaric and I must admit that that helped the girl with whom I spoke, even though things were not going so well, decided to accompany the sexologist. It was the first time he had mentioned to her. The doctor advised me to read a book which reassured me a lot and face a therapy to which she sometimes came too. The truth is quite the thing improved in the sense that I gave more time because I got so mad. But I tell you that was costing me, I always lacked a little bit of stiffness or down before me. At that time the doctor suggested I also used the Viagra therapy. Yet I Candomble dead heart and I said no, but he told me the truth of things that did not act on the heart as well as I played football told me that a sexual act is less demanding for the heart than a party. Also do not smoke and I have the Anáslisis well. I was not convinced because, well, at my age would be taking viagra ... but also that the office had seen were boys younger than me, bah do not know if it was about the same problem.

To reassure the sexologist I proposed that we test in the same office: I went one day, gave me the pill, I took the pressure, pulse, I sounded ... Aviv that I did to leave me alone. I even explained that he needed it at all and that it was because I was scared (it was the truth). I saw that I did nothing wrong, just felt a little warmth in the face and ears and a little congestion in the nose, I decided to use her.
He told me to wear it with belly vacuum without alcohol and it took half an hour earlier and give me time for foreplay. My girl knew she had taken. That day I felt like power, and it worked barbarian ... I make it last longer and enjoy it. I had a huge stiff, like those that I take every morning when I wake up. After that use him again a couple of times and always very well with the 50 mg. Once I had sex without the pill and went well. Now I'm alternating the idea but I stop taking it and continue with the therapy that the sex therapist told me it would be a few more sessions. If some day he will need to use the pill, but I'll take care of myself, I feel I gained security, which was what I needed, but also learned things that medication alone did not, I mean what I read what I taught the treatment and what helped me this pair, which is not the love of my life, but I want to follow it.